Compare prices across discount programs and pharmacies
Last Updated: January 2026
| Medication Name | Type | Typical Retail Price | Best Coupon Price (2026) | Lowest Source |
|---|---|---|---|---|
|
Estradiol (Generic)
1mg or 2mg tablets
|
Pills | $200-300/month $10-50/month |
$5-15/month Save up to 90% |
Optum Perks |
|
Estrace
Estradiol tablets
|
Pills | $200-300/month |
$160-180/month Save up to 45% |
BuzzRx |
|
Premarin
Conjugated estrogens
|
Pills | $250-280/month |
$80-200/month Save up to 70% |
SingleCare |
|
Estradiol Patches (Generic)
Twice weekly or weekly
|
Patches | $210-350/month $180-250/month |
$35-65/month Save up to 86% |
GoodRx |
|
Vivelle-Dot
Brand estradiol patch
|
Patches | $210-300/month |
$20-70/month Save up to 90% |
BuzzRx |
|
Climara
Weekly estradiol patch
|
Patches | $220-350/month |
$25-40/month Save up to 90% |
Hippo |
|
Topical Gels (Generic)
Estradiol gel packets
|
Gel | $200-510/month $70-350/month |
$40-120/month Save up to 86% |
Hippo |
|
EstroGel
Estradiol gel pump
|
Gel | $260-510/month |
$160-190/month Save up to 68% |
BuzzRx |
|
Divigel
Estradiol gel packets
|
Gel | $200-300/month |
$110-190/month Save up to 63% |
BuzzRx |
|
Bijuva
Estradiol + progesterone capsules
|
Combination | $300-450/month |
$85-230/month Save up to 81% |
GoodRx |
|
CombiPatch
Estradiol + norethindrone patch
|
Combination | $310-400/month |
$250-300/month Save up to 37% |
BuzzRx |
|
Climara Pro
Estradiol + levonorgestrel patch
|
Combination | $310-450/month |
$240-290/month Save up to 47% |
Optum Perks |
|
Activella
Estradiol + norethindrone tablets
|
Combination | $300-400/month |
$32-295/month Save up to 90% |
Optum Perks |
|
Prempro
Conjugated estrogens + medroxyprogesterone
|
Combination | $200-350/month |
$100-140/month Save up to 70% |
GoodRx |
|
Progesterone (Generic)
Micronized progesterone capsules
|
Pills | $485-530/month $80-150/month |
$15-35/month Save up to 81% |
Cost Plus Drugs |
|
Prometrium
Brand progesterone capsules
|
Pills | $485-530/month |
$335-450/month Save up to 37% |
GoodRx |
|
Estradiol Cream (Generic)
Estradiol vaginal cream
|
Vaginal | $190-450/month $110-290/month |
$20-80/month Save up to 90% |
Cost Plus Drugs |
|
Vagifem
Estradiol vaginal tablets
|
Vaginal | $200-280/month |
$140-190/month Save up to 50% |
SingleCare |
|
Yuvafem
Generic vaginal estradiol tablets
|
Vaginal | $190-200/month |
$45-75/month Save up to 78% |
SingleCare |
|
Estrace Vaginal Cream
Estradiol vaginal cream
|
Vaginal | $400-450/tube |
$340-380/tube Save up to 24% |
Hippo |
|
Imvexxy
Low-dose vaginal estradiol inserts
|
Vaginal | $250-300/month |
$85-180/month Save up to 72% |
GoodRx |
| Medication (Generic/Brand) | Treatment | BuzzRx | GoodRx | Hippo | Optum Perks | SingleCare |
|---|---|---|---|---|---|---|
| Estradiol / levonorgestrel (Climara Pro) | Vaginal & Vasomotor | |||||
| Estradiol / norethindrone (Combipatch) | Vaginal & Vasomotor |
| Medication (Generic/Brand) | BuzzRx | GoodRx | Hippo | Optum Perks | SingleCare | |
|---|---|---|---|---|---|---|
| Micronized natural progesterone / Prometrium | ||||||
| Synthetic progestin / Medroxyprogesterone (Provera) |