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Symptom Relief

Current HRT Price Snapshots

Compare prices across discount programs and pharmacies

Last Updated: January 2026

Filter by type:
Medication Name Type Typical Retail Price Best Coupon Price (2026) Lowest Source
Estradiol (Generic)
1mg or 2mg tablets
Pills $200-300/month $10-50/month $5-15/month
Save up to 90%
🟠 Optum Perks
Estrace
Estradiol tablets
Pills $200-300/month $160-180/month
Save up to 45%
🐝 BuzzRx
Premarin
Conjugated estrogens
Pills $250-280/month $80-200/month
Save up to 70%
💳 SingleCare
Estradiol Patches (Generic)
Twice weekly or weekly
Patches $210-350/month $180-250/month $35-65/month
Save up to 86%
🏷️ GoodRx
Vivelle-Dot
Brand estradiol patch
Patches $210-300/month $20-70/month
Save up to 90%
🐝 BuzzRx
Climara
Weekly estradiol patch
Patches $220-350/month $25-40/month
Save up to 90%
🟩 Hippo
Topical Gels (Generic)
Estradiol gel packets
Gel $200-510/month $70-350/month $40-120/month
Save up to 86%
🟩 Hippo
EstroGel
Estradiol gel pump
Gel $260-510/month $160-190/month
Save up to 68%
🐝 BuzzRx
Divigel
Estradiol gel packets
Gel $200-300/month $110-190/month
Save up to 63%
🐝 BuzzRx
Bijuva
Estradiol + progesterone capsules
Combination $300-450/month $85-230/month
Save up to 81%
🏷️ GoodRx
CombiPatch
Estradiol + norethindrone patch
Combination $310-400/month $250-300/month
Save up to 37%
🐝 BuzzRx
Climara Pro
Estradiol + levonorgestrel patch
Combination $310-450/month $240-290/month
Save up to 47%
🟠 Optum Perks
Activella
Estradiol + norethindrone tablets
Combination $300-400/month $32-295/month
Save up to 90%
🟠 Optum Perks
Prempro
Conjugated estrogens + medroxyprogesterone
Combination $200-350/month $100-140/month
Save up to 70%
🏷️ GoodRx
Progesterone (Generic)
Micronized progesterone capsules
Pills $485-530/month $80-150/month $15-35/month
Save up to 81%
💊 Cost Plus Drugs
Prometrium
Brand progesterone capsules
Pills $485-530/month $335-450/month
Save up to 37%
🏷️ GoodRx
Estradiol Cream (Generic)
Estradiol vaginal cream
Vaginal $190-450/month $110-290/month $20-80/month
Save up to 90%
💊 Cost Plus Drugs
Vagifem
Estradiol vaginal tablets
Vaginal $200-280/month $140-190/month
Save up to 50%
💳 SingleCare
Yuvafem
Generic vaginal estradiol tablets
Vaginal $190-200/month $45-75/month
Save up to 78%
💳 SingleCare
Estrace Vaginal Cream
Estradiol vaginal cream
Vaginal $400-450/tube $340-380/tube
Save up to 24%
🟩 Hippo
Imvexxy
Low-dose vaginal estradiol inserts
Vaginal $250-300/month $85-180/month
Save up to 72%
🏷️ GoodRx
💡 Important Notes: Prices shown are estimates based on January 2026 data and vary by location, pharmacy, dosage, and quantity. Always check current prices at the source links before purchasing. Coupon prices typically require no insurance and can often beat insurance copays. For manufacturer copay cards and patient assistance programs, see the detailed sections below.

Estrogen patches
Medication (Generic/Brand) Treatment BuzzRx GoodRx Hippo Optum Perks SingleCare
Estradiol patch once-weekly (Climara) Vaginal & Vasomotor
Estradiol patch twice-weekly (Dotti, Vivelle-Dot) Vaginal & Vasomotor
Combination estrogen / progestogen patches
Medication (Generic/Brand) Treatment BuzzRx GoodRx Hippo Optum Perks SingleCare
Estradiol / levonorgestrel (Climara Pro) Vaginal & Vasomotor
Estradiol / norethindrone (Combipatch) Vaginal & Vasomotor
Vaginal estrogen
Medication (Generic/Brand) Treatment BuzzRx GoodRx Hippo Optum Perks SingleCare
Estradiol vaginal cream (Estrace) Vaginal
Conjugated estrogens vaginal cream (Premarin cream) Vaginal
Estradiol vaginal tablets (Yuvafem, Vagifem) Vaginal
Estradiol vaginal ring (Estring) Vaginal
Estradiol vaginal ring (Femring) Vaginal & Vasomotor
Oral combination pills
Medication (Generic/Brand) BuzzRx GoodRx Hippo Optum Perks SingleCare
Estradiol / norethindrone (Mimvey, Loprezza, Activella)
Estradiol / norethindrone-eth (Fyavolv, Jinteli, Femhrt, Jevantique)
Estradiol / progesterone (Bijuva)
Conjugated estrogens / medroxyprogesterone (Prempro, Premphase)
Conjugated estrogens / bazedoxifene (Duavee)
Topical estrogen or testosterone gel or spray
Medication (Generic/Brand) Treatment BuzzRx GoodRx Hippo Optum Perks SingleCare
Estradiol gel single-use packets (Divigel) Vasomotor
Estradiol spray (Evamist) Vasomotor
Estradiol gel metered-dose pump (Estrogel) Vaginal & Vasomotor
Testosterone gel metered-dose pump (Androgel, Axiron, Fortesta, Testim, Vogelxo)
Oral progestogens
Medication (Generic/Brand) BuzzRx GoodRx Hippo Optum Perks SingleCare
Micronized natural progesterone / Prometrium
Synthetic progestin / Medroxyprogesterone (Provera)
Nonhormonal menopause medications
Medication (Generic/Brand) Treatment BuzzRx GoodRx Hippo Optum Perks SingleCare
Prasterone Vaginal DHEA derivative insert (Intrarosa) Vaginal
Ospemifene Oral SERM (Osphena) Vaginal
Pareoxetine Oral SSRI Paroxetine Mesylate (Brisdelle) Vasomotor
Fezolinetant Oral NK3 antagonist (Veozah) Vasomotor
Medications sometimes prescribed off-label to manage vasomotor symptoms
Medication (Generic/Brand) BuzzRx GoodRx Hippo Optum Perks SingleCare
Gabapentin (Gralise, Neurontin)
Venlafaxine (Effexor)
Clonidine (Catapres, Catapres-Tts)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Amitriptyline (Amitid, Amitril, and Elavil, Endep)
Bupropion (Wellbutrin)
Desvenlafaxine (Khedezla)
Duloxetine (Cymbalta)
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