Menopause medications—whether hormonal, non-hormonal, or over-the-counter—can cost anywhere from $20 to $600+ per month. But here's what most doctors won't tell you: your insurance copay is often MORE expensive than using a coupon.
We've built this comprehensive guide to help you find the lowest prices on every type of menopause medication and supplement. Whether you're on hormone replacement therapy (HRT), taking Veozah for hot flashes, or using OTC supplements like Estroven, we'll show you exactly where to find savings.
Compare prices across discount programs and pharmacies
Last Updated: January 2026
| Medication Name | Type | Typical Retail Price | Best Coupon Price (2026) | Lowest Source |
|---|---|---|---|---|
|
Estradiol (Generic)
1mg or 2mg tablets
|
Pills | $200-300/month $10-50/month |
$5-15/month Save up to 90% |
Optum Perks |
|
Estrace
Estradiol tablets
|
Pills | $200-300/month |
$160-180/month Save up to 45% |
BuzzRx |
|
Premarin
Conjugated estrogens
|
Pills | $250-280/month |
$80-200/month Save up to 70% |
SingleCare |
|
Estradiol Patches (Generic)
Twice weekly or weekly
|
Patches | $210-350/month $180-250/month |
$35-65/month Save up to 86% |
GoodRx |
|
Vivelle-Dot
Brand estradiol patch
|
Patches | $210-300/month |
$20-70/month Save up to 90% |
BuzzRx |
|
Climara
Weekly estradiol patch
|
Patches | $220-350/month |
$25-40/month Save up to 90% |
Hippo |
|
Topical Gels (Generic)
Estradiol gel packets
|
Gel | $200-510/month $70-350/month |
$40-120/month Save up to 86% |
Hippo |
|
EstroGel
Estradiol gel pump
|
Gel | $260-510/month |
$160-190/month Save up to 68% |
BuzzRx |
|
Divigel
Estradiol gel packets
|
Gel | $200-300/month |
$110-190/month Save up to 63% |
BuzzRx |
|
Bijuva
Estradiol + progesterone capsules
|
Combination | $300-450/month |
$85-230/month Save up to 81% |
GoodRx |
|
CombiPatch
Estradiol + norethindrone patch
|
Combination | $310-400/month |
$250-300/month Save up to 37% |
BuzzRx |
|
Climara Pro
Estradiol + levonorgestrel patch
|
Combination | $310-450/month |
$240-290/month Save up to 47% |
Optum Perks |
|
Activella
Estradiol + norethindrone tablets
|
Combination | $300-400/month |
$32-295/month Save up to 90% |
Optum Perks |
|
Prempro
Conjugated estrogens + medroxyprogesterone
|
Combination | $200-350/month |
$100-140/month Save up to 70% |
GoodRx |
|
Progesterone (Generic)
Micronized progesterone capsules
|
Pills | $485-530/month $80-150/month |
$15-35/month Save up to 81% |
Cost Plus Drugs |
|
Prometrium
Brand progesterone capsules
|
Pills | $485-530/month |
$335-450/month Save up to 37% |
GoodRx |
|
Estradiol Cream (Generic)
Estradiol vaginal cream
|
Vaginal | $190-450/month $110-290/month |
$20-80/month Save up to 90% |
Cost Plus Drugs |
|
Vagifem
Estradiol vaginal tablets
|
Vaginal | $200-280/month |
$140-190/month Save up to 50% |
SingleCare |
|
Yuvafem
Generic vaginal estradiol tablets
|
Vaginal | $190-200/month |
$45-75/month Save up to 78% |
SingleCare |
|
Estrace Vaginal Cream
Estradiol vaginal cream
|
Vaginal | $400-450/tube |
$340-380/tube Save up to 24% |
Hippo |
|
Imvexxy
Low-dose vaginal estradiol inserts
|
Vaginal | $250-300/month |
$85-180/month Save up to 72% |
GoodRx |
Step 1: Find your medication in the table below
Step 2: Click through to 2-3 discount sites
Step 3: Enter your ZIP code and dosage
Step 4: Compare prices across your local pharmacies
Step 5: Show the coupon code to your pharmacist
Pro Tips:
What if my medication isn't listed?
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💡 Pro Tip: Scroll down to find your specific medication, or use Ctrl+F (Cmd+F on Mac) to search this page for your medication name.
| Medication (Generic/Brand) | Treatment | BuzzRx | GoodRx | Hippo | Optum Perks | SingleCare |
|---|---|---|---|---|---|---|
| Estradiol / levonorgestrel (Climara Pro) | Vaginal & Vasomotor | |||||
| Estradiol / norethindrone (Combipatch) | Vaginal & Vasomotor |
| Medication (Generic/Brand) | BuzzRx | GoodRx | Hippo | Optum Perks | SingleCare | |
|---|---|---|---|---|---|---|
| Micronized natural progesterone / Prometrium | ||||||
| Synthetic progestin / Medroxyprogesterone (Provera) |
Can't or don't want to take hormones? These FDA-approved alternatives can help.
What it is: First FDA-approved non-hormonal prescription for hot flashes
Average retail price: $550-650/month
With coupons: $300-400/month
With manufacturer savings: $0-25/month for eligible patients
Important: Veozah requires liver function monitoring. Your first 3 months may include blood test costs (~$30-50 each).
Learn more about Veozah and other how drugs like Lynkuet are revolutionizing the non-hormonal treatment of hot flashes and night sweats.
What it is: SSRI antidepressant, FDA-approved at low doses for vasomotor symptoms
Average cost: $10-40/month with coupons
Generic available: Yes (paroxetine)
What it is: Nerve pain medication used off-label for menopause
Average cost: $10-30/month with coupons
Prescription required: Yes
These don't require prescriptions but can still add up quickly.
What it is: Black cohosh + soy isoflavones supplement
Retail price: $25-35/month
Where to save:
FSA/HSA Eligible? ❌ No, unless prescribed by doctor
What it is: Standardized black cohosh for hot flashes
Retail price: $15-25/month
Where to save:
FSA/HSA Eligible? ❌ No, unless prescribed
Retail price: $12-20/month
Where to save: Generic store brands work just as well
Learn more about natural alternatives to help manage menopause and perimenopause symptoms.
For vaginal dryness, painful sex, and urinary symptoms. Often covered separately from systemic HRT.
Average price: $250-350/month without insurance
With coupons: $80-150/month
Average price: $80-120/month
Much cheaper alternative to brand-name
Average price: $100-200/tube
Generic version: Yes, much cheaper
Many women experience significant changes in vaginal, vulvar, and urinary health during perimenopause and menopause. These changes, while common, can feel isolating or even embarrassing to discuss. These articles shed light on these issues, explain their causes, and explore effective solutions.
Often overlooked but critical for energy, libido, and muscle maintenance during menopause.
Note: No FDA-approved testosterone products for women exist in the US. Most use low-dose men's products or compounded versions.
Average cost: $50-150/month
Where to save on Testosterone:
Further your understanding of how changes in testosterone affect women in menopause and perimenopause.
Birth control pills are often prescribed during perimenopause to regulate periods and ease symptoms.
These programs can reduce your out-of-pocket costs to $0-25/month if you have commercial insurance.
Note on Jevantique & Fyavolv:
⚠️ These are generic HRT medications (ethinyl estradiol/norethindrone). As generic drugs, they typically do NOT have manufacturer copay programs. However, they're often very affordable:
Important: Most manufacturer copay cards ONLY work with commercial insurance, not:
We’ve broken down the real costs of menopause treatment options—from hormone replacement therapy to non-hormonal medications, supplements, and alternative therapies. Find out how to access the lowest prices, regardless of your insurance situation at:
Most programs require:
❌ Medicare Part D - Federal law prohibits manufacturer assistance
❌ Medicaid - Government program exclusion
❌ Tricare - Military insurance exclusion
❌ VA Benefits - Veterans health program exclusion
❌ Cash-pay patients (insurance that doesn't cover the drug at all)
Alternative for these patients: Look for Patient Assistance Programs (PAPs) - see below
If you CAN'T use copay cards, these programs may provide free or low-cost medication:
Since Medicare patients can't use copay cards, try these:
Most PAPs require household income below these levels:
| Household Size | Annual Income Limit (approx.) |
|---|---|
| 1 person | $30,000-60,000 |
| 2 people | $40,000-80,000 |
| 3 people | $50,000-100,000 |
| 4 people | $60,000-120,000 |
Limits vary by manufacturer and program. Some are more generous than others.
Not all menopause products qualify for tax-advantaged spending. Here's what does and doesn't.
Note: Some items become eligible with a Letter of Medical Necessity (LMN) from your doctor. Ask your FSA administrator which items qualify.
Are pads/tampons FSA eligible?
✅ YES, as of 2020! The CARES Act made menstrual products FSA/HSA eligible without a prescription.
This includes:
If you don't have insurance OR your copay is too high, try these:
Insurance companies negotiate different prices with different pharmacies. Your copay may be based on the "list price" rather than the negotiated rate. Using a coupon bypasses insurance entirely and accesses a different pricing structure.
Action: Always ask your pharmacist to price it BOTH ways.
❌ No. Federal law prohibits manufacturer copay cards for Medicare Part D patients. However, you may qualify for:
❌ No. When you use a discount coupon instead of insurance, that purchase does NOT count toward your insurance deductible or out-of-pocket maximum.
However: This may still save you money! Example:
✅ YES! That's exactly how they're designed to work. The card covers your copay amount after insurance processes the claim.
Usually, but not always. Sometimes brand-name medications have better manufacturer coupons that make them cheaper than generic. Always compare both.
Prices can change monthly or even weekly. Best practice: Check prices each time you refill, especially if you're cash-paying.
Many women find telemedicine services more convenient AND often more affordable than traditional care. Here's a breakdown:
| Service | Monthly Cost | Meds Included? | Insurance? | Best For |
|---|---|---|---|---|
| Fountain HRT | $199 | ✅ Yes | ❌ No | All-in-one, no surprises |
| Joi | $50 | ✅ Yes | ❌ No | Testosterone access |
| Evernow | $35–49 | ❌ No | ✅ Yes | Ongoing support |
| Midi | $250 initial | ❌ No | ✅ Yes | Insurance coverage |
| PlushCare | $20 + visit | ❌ No | ✅ Yes | Same-day care |
| Gennev | Per visit | ❌ No | ✅ Yes | Pay-as-you-go |
Price accuracy: Medication prices listed are estimates based on average retail prices as of January 19, 2026. Actual prices vary by pharmacy, location, insurance, and dosage. Always verify current pricing before purchasing.
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